Publications

A Complete List of Published NIH-Funded Work can also be found in here

2018 Journal Articles

Cofactors are essential constituents of stable and seeding-active tau fibrils
Y. Fichou, Y. Lin, J. N. Rauch, M. Vigers, Z. Zeng, M. Srivastava, T. J. Keller, J. H. Freed, K. S. Kosik, S. Han. Proc. Nat. Acad. Sci. (2018).
DOI: 10.1073/pnas.1810058115

Highlighted in the UC Santa Barbara Current:
http://www.news.ucsb.edu/2018/019293/three-player-game

Effect of nitroxide spin probes on the transport properties of Nafion membranes
T. Überrück, O. Neudert, K.-D. Kreuer, B. Blümich, J. Granwehr, S. Stapf, S. Han. Phys. Chem. Chem. Phys., 20 (2018), 26660-26674.
DOI: 10.1039/C8CP04607G

Maximizing NMR signal per unit time by facilitating the e-e-n cross effect DNP rate
A. Leavesley, S. Jain, I. Kaminker, H. Zhang, S. Rajca, A. Rajca, S. Han. Phys. Chem. Chem. Phys. 20 (2018), 27646-27654.
DOI: 10.1039/C8CP04909B

Selected 2018 PCCP Hot Article 

Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions
Y. Lin, J. McCarty, J. N. Rauch, K. T. Delaney, K. S. Kosik, G. H. Fredrickson, J.-E. Shea, S. Han.  bioRxiv (2018).
DOI: 10.1101/424358
Tuning nuclear depolarization under MAS by electron T1e
A. Lund, A. Equibal, S. Han.  Phys. Chem. Chem. Phys. 20 (2018), 23976-23987.
DOI: 10.1039/C8CP04167A

Heterogeneity of network structure and water dynamics in κ-carrageenan gels probed by nanoparticle diffusometry
D. de Kort, E. Schuster, F. Hoeben, R. Barnes, M. Emondts, H. Janssen, N. Lorén, S. Han, H. van As, J. van Duynhoven.  Langmuir, 34 (37) (2018), 11110-11120.
DOI: 10.1021/acs.langmuir.8b01052

Multi-step phase-cycling in a free-electron laser-powered pulsed electron paramagnetic resonance spectrometer
C. B. Wilson, S. Aronson, J. A. Clayton, S. J. Glaser, S. Han, M. S. Sherwin. Phys. Chem. Chem. Phys., 20 (2018), 18097-18109.
DOI: 10.1039/C8CP01876F
Amplification of Dynamic Nuclear Polarization at 200 GHz by Arbitrary Pulse Shaping of the Electron Spin Saturation Profile
I. Kaminker, S. Han. J. Phys. Chem. Lett., 9 (11) (2018), 3110-3115.
DOI: 10.1021/acs.jpclett.8b01413
Tuning conformation and properties of peptidomimetic backbones through dual N/Cα-substitution
R. Kaminker, I. Kaminker, W. R. Gutekunst, Y. Luo, S. Lee, J. Niu, S. Han, C. J. Hawker. Chem. Comm., 54 (41) (2018), 5237-5240.
DOI: 10.1039/C8CC01356J
Truncated Cross Effect Dynamic Nuclear Polarization: An Overhauser Effect Doppelgänger
A. Equbal, Y. Li, A. Leavesley, S. Huang, S. Rajca, A. Rajca, S. Han, J. Phys. Chem. Lett., (9) (2018), 2175-2180.
DOI: 10.1021/acs.jpclett.8b00751
Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer’s disease filaments
Y. Fichou, M. Vigers, A. K. Goring, N. A. Eschmann, S. Han, Chem. Commun., 54 (36) (2018), 4573-4576.
DOI: 10.1039/C8CC01355Aa
Quantitative analysis of zero-field splitting parameter distributions in Gd(III) complexes
J. A. Clayton, K. Keller, M. Qi, J. Wegner, V. Koch, H. Hintz, A. Godt, S. Han, G. Jeschke, M. S. Sherwin, M. Yulikov, Phys. Chem. Chem. Phys.20 (15) (2018)10470-10492. PubMed PMID: 29617015; PubMed Central PMCID: PMC6026474. 
DOI: 10.1039/c7cp08507a

Functionally Active Membrane Proteins Incorporated in Mesostructured Silica Films
J. P. Jahnke, M. N. Idso, S. Hussain, M. J. N. Junk, J. M. Fisher, D. D. Phan, S. Han, B. F. Chmelka, J. Am. Chem. Soc., 140 (11) (2018), 3892-3906.
DOI:10.1021/jacs.7b06863 PMID: 29533066.

Effect of Water/Glycerol Polymorphism on Dynamic Nuclear Polarization  
A. Leavesley, C. B. Wilson, M. Sherwin, S. Han, Phys. Chem. Chem. Phys20 (15) (2018), 9897-9903.
DOI:10.1039/C8CP00358K

Reversal of Paramagnetic Effects by Electron Spin Saturation 
S. K. Jain, T. A. Siaw, A. Equbal, C. B. Wilson, I. Kaminker, S. Han, J. Phys. Chem. C122 (10) (2018), 5578-5589.
DOI:10.1021/acs.jpcc.8b00312

Surface Chemical Heterogeneity Modulates Silica Surface Hydration 
A. M. Schrader, J. I. Monroe, R. Sheil, H. A. Dobbs, T. J. Keller, Y. Li, S. Jain, M. S. Shell, J. V. Israelachvili, S. Han, Proc. Natl. Acad. Sci. U.S.A.115 (12) (2018) 2890-2895.
DOI:10.1073/pnas.1722263115

Highlighted in the UC Santa Barbara Current: 
http://www.news.ucsb.edu/2018/018793/glass-matters
View PDF file

Perspective of Overhauser Dynamic Nuclear Polarization for the Study of Soft Materials 
R. Barnes, S. Han, J. Biller, Curr. Opin. Colloid Interface Sci., 33 (2018), 72-85.
DOI:10.1016/j.cocis.2018.02.007

2017 Journal Articles

Spatially Heterogeneous Surface Water Diffusivity around Structured Protein Surfaces at Equilibrium
R. Barnes, S. Sun, Y. Fichou, F.W. Dahlquist, M. Heyden, S. Han, J. Am. Chem. Soc., 139 (49) (2017) 17890-17901.
DOI:10.1021/jacs.7b08606

Highlighted Cover Article: http://pubs.acs.org/toc/jacsat/139/49

Simple peptide coacervates adapted for rapid pressure-sensitive wet adhesion
I. Kaminker, W. Wei, A.M. Schrader, Y. Talmon, M.T. Valentine, J.N. Israelachvili, J.H. Waite, S. Han, Soft Matter., 13 (48) (2017) 9122-9131.
DOI:10.1039/C7SM01915G

Universal Dynamics of Molecular Reorientation in Hybrid Lead Iodide Perovskites
D.H Fabini, T.A. Siaw, C.C. Stoumpos, G. Laurita, D. Olds, K. Page, J.G. Hu, M.G. Kanatzidis, S. Han, R. Seshadri, J. Am. Chem. Soc., 139 (46) (2017) 16875-16884.
DOI:10.1021/jacs.7b09536

Highlighted Cover Article: http://pubs.acs.org/toc/jacsat/139/46

Conformation-based assay of tau protein aggregation
Y. Fichou, N.A. Eschmann, T.J. Keller, S. Han, Methods Cell Biol., 141 (2017) 89-112.
DOI:10.1016/bs.mcb.2017.06.008

Proton-based structural analysis of heptahelical transmembrane protein in lipid bilayers
D. Lalli, M.N. Idso, L.B. Andreas, S. Hussain, N. Baxter, S. Han, B. Chmelka, G. Pintacuda, J. Am. Chem. Soc., 139 (37) (2017) 13006-13012.
DOI:10.1021/jacs.7b02969 PubMed PMID: 28724288; PubMed Central PMCID: PMC5741281.

Highlighted Cover Article: http://pubs.acs.org/toc/jacsat/139/37

Water Dynamics from the Surface to the Interior of a Supramolecular Nanostructure
J.H. Ortony, B. Qiao, C.J. Newcomb, T.J. Keller, L.C. Palmer, E. Deiss-Yehiely, M.O. Cruz S. Han, S.I. Stupp, J. Am. Chem. Soc., 139 (26) (2017) 8915–8921
DOI:10.1021/jacs.7b02969

Highlighted in Nature Chemistry News and Views: http://doi.org/10.1038/nchem.2870

 

RNA Stores Tau Reversibly in Complex Coacervates
X. Zhang, N.E. Eschmann, Y. Lin, H. Zhou, J. Rauch, I. Hernandez, E. Guzman, K.S. Kosik, S. Han, PLOS Biol., 15 (7(2017) e2002183.
DOI:10.1371/journal.pbio.2002183. PMID: 28683104. PMCID: PMC5500003

Also published in bioRxiv:
DOI:10.1016/



http://www.news.ucsb.edu/2017/018072/biophysical-smoking-gun

Arbitrary waveform modulated pulse EPR at 200 GHz
I. Kaminker, R. Barnes, S. Han, J. Magn. Reson., 279 (2017) 81-90
DOI:10.1016/j.jmr.2017.04.016PMID: 28482216. PMCID: PMC5519772

Signature of an aggregation-prone conformation of tau
N.A. Eschmann, E.R. Georgieva, P. Ganguly, P.P. Borbat, M.D. Rappaport, Y. Akdogan, J.H. Freed, J.E. Shea, S. Han, Sci. Rep., 7 (2017) 1-10
DOI:10.1038/srep44739. PMID: 28303942. PMCID: PMC5356194

Gd3+-Gd3+ distances exceeding 3 nm determined by very high frequency continuous wave electron paramagnetic resonance
J.A. Clayton, M. Qi, A. Godt, D. Goldfarb, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 19 (7) (2017) 5127-5136
DOI:10.1039/C6CP07119H. PMID: 28139788. PMCID: PMC5394103

Effect of electron spectral diffusion on static dynamic nuclear polarization at 7 Tesla
A. Leavesley, D. Shimon, T. Siaw, A. Feintuch, D. Goldfarb, S. Vega, I. Kaminker, S. Han, Phys. Chem. Chem. Phys., 19 (5) (2017) 3596-3605.
DOI:10.1039/C6CP06893F. PMID: 28094364

2016 Journal Articles

Hydration dynamics of a peripheral membrane protein
O. Fisette, C. Paslack, R. Barnes, J.M. Isas, R. Langen, M. Heyden, S. Han, L.V. Schafer, J. Am Chem. Soc., 138 (2016) 11526-11535
DOI:10.1021/jacs.6b07005  PubMed PMID: 27548572; PubMed Central PMCID: PMC5519773.

Adenosine A2a receptors form distinc oligomers in protein detergent complexes
N.S. Schonenbach, M.D. Rieth, S. Han, M.A. O'Malley, FEBS Lett., 590 (2016) 3295–3306
DOI:10.1002/1873-3468.12367 PubMed PMID: 27543907; PubMed Central PMCID: PMC5039092.

Contrasting Effects of Glycerol and DMSO on Lipid Membrane Surface Hydration Dynamics and Forces
A. Schrader, C. Cheng, J. Israelachvili, S. Han, J. Chem. Phys., 145 (2016) 041101
DOI:10.1063/1.4959904 PubMed PMID: 27475340; PubMed Central PMCID: PMC4967073.

Molecular and structural basis of low interfacial energy of complex coacervates in water
Y. Jho, H. Yoo, Y. Lin, S. Han, D. Hwang, Adv. Colloid Interface Sci., 239 (2017) 61–73
DOI:10.1016/j.cis.2016.07.003. PMID: 27499328.

Biocontinuous Fluid Structure with Low Cohesive Energy: Molecular Basis for Exceptionally Low Interfacial Tension of Complex Coacervate Fluids
K. Huang, H. Yoo, Y. Jho, S. Han, D. Hwang, ACS Nano, 10 (2016) 5051-5062
DOI:10.1021/acsnano.5b07787
Stability of protein-specific hydration shell on crowding
K. Huang, C.N. Kingsley, R. Sheil, C. Cheng, J.B. Bierma, K.W. Roskamp, D. Khago, R.W. Martin, S. Han, J. Am. Chem. Soc., 138 (16) (2016) 5392–5402
DOI:10.1021/jacs.6b01989 PubMed PMID: 27052457.
A versatile and modular quasi optics-based 200 GHz dual dynamic nuclear polarization and electron paramagnetic resonance instrument
T.A. Siaw, A. Leavesley, A. Lund, I. Kaminker, S. Han, J. Magn. Reson., 264  (2016) 131-153
PMCID: ​PMC4770585
DOI:10.1016/j.jmr.2015.12.012
Protein structural and surface water rearrangement constitute major events in the earliest aggregation stages of tau
A. Pavlova, C. Cheng, M. Kinnebrew, J. Lew, F. Dahlquist, S. Han, Proc. Natl. Acad. Sci., 113 (2) (2016) E127-E136
PMCID: PMC4720316
DOI:10.1073/pnas.1504415113 

2015 Journal Articles

Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?
P. Stals, C. Cheng, L. Beek, A. Wauters, A. Palmans, S. Han, E. Meijer, Chem. Sci., 7 (2015) 2011-2015
DOI: 10.1039/C5SC02319J
Tau Aggregation Propensity Engrained in Its Solution State
N. Eschmann, T. Do, N. LaPointe, J. Shea, S. Feinstein, M. Bowers, S. Han, J. Phys. Chem., 119 (45) (2015) 14421–14432
PMID: 26484390; PMCID: PMC4645975
DOI: 10.1021/acs.jpcb.5b08092 
Mussel Coating Protein-Derived Complex Coacervates Mitigate Frictional Surface Damage
D. Miller, S. Das, K. Huang, S. Han, J. Israelachvili, J. Waite, ACS Biomater. Sci. Eng., 1 (11) (2015) 1121–1128
PMID: 26618194; PMCID: PMC4642218
DOI:10.1021/acsbiomaterials.5b00252 
ACS Editors' Choice Paper
Direct Dynamic Nuclear Polarization Targeting Catalytically Active 27Al Sites
A. Lund, M. Hsieh, T. Siaw, S. Han, Phys. Chem. Chem. Phys., 17 (2015) 25449-25454
PMID: 26365719
DOI:10.1039/C5CP03396A 
Anomalously rapid hydration water diffusion dynamics near DNA surfaces
J. Franck, Y. Ding, K. Stone, P. Qin, S. Han, J. Am. Chem. Soc., 137 (37) (2015) 12013-12023
PMID: 26256693; PMCID: PMC4656248
DOI: 10.1021/jacs.5b05813
Correlating steric-hydration forces with water dynamics through surface force and diffusion NMR measurements in a lipid-DMSO-H2O system
A. Schrader, S. Donaldson, J. Song, C. Cheng, D. Lee, S. Han, J. Israelachvili, Proc. Natl. Acad. Sci., 112 (34) (2015) 10708–10713
PMID: 26261313; PMCID: PMC4553805
DOI: 10.1073/pnas.1512325112  
Active Cancellation - A Means to Zero Dead-Time Pulse EPR
J. Franck, R. Barnes, T. Keller, T. Kaufmann, S. Han, J. Magn. Reson., 261 (2015) 199-204
PMID: 26507308; PMCID: PMC4688155
DOI: 10.1016/j.jmr.2015.07.005
DMSO induces dehydration near lipid membrane surfaces
C. Cheng, J. Song, J. Pas, L. Meijer, S. Han, Biophys. J., 109 (2) (2015) 330-339
PMID: 26200868; PMCID: PMC4621616
DOI: 10.1016/j.bpj.2015.06.011
Ion specific effects: decoupling ion-ion and ion-water interactions
J. Song, M. Kim, T. Kang, S. Han, Phys. Chem. Chem. Phys., 17 (2015) 8306-8322
PMID: 25761273; PMCID: PMC4656249
DOI: 10.1039/C4CP05992A
Functional Consequences of the Oligomeric Assembly of Proteorhodopsin
S. Hussain, M. Kinnebrew, N. Schonenbach, E. Aye, S. Han, J. Molec. Biol., 427 (6B) (2015) 1278-1290
PMID: 25597999; PMCID: PMC4374980
DOI: 10.1016/j.jmb.2015.01.004
Nanometer-Scale Water and Proton Diffusion Heterogeneities across Water Channels in Polymer Electrolyte Membranes
J. Song, O. H. Han,  S. Han, Angew. Chem., 54 (12) (2015) 3615-3620
PMID: 25630609; PMCID: PMC4450673
DOI: 10.1002/anie.201408318

2015 Book Chapters

Methods in Enzymology: Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions - Part B
Edited by: P. Z. Qin, K. Warncke

Vol. 564, Elsevier Inc. (2015)

Overhauser Dynamic Nuclear Polarization Studies on Local Water Dynamics
I. Kaminker, R. Barnes, and S. Han
PMID: 26477261
DOI: 10.1016/bs.mie.2015.06.040

Protein NMR - Modern Techniques and Biomedical Applications
Edited by: Lawrence Berliner

Vol. 32, Springer (2015) 43-74

Mapping Out Protein Hydration Dynamics by Overhauser Dynamic Nuclear Polarization
C. Cheng, J. Song, J. Franck, S. Han
DOI: 10.1007/978-1-4899-7621-5_2

2014 Journal Articles

Local water diffusivity as a molecular probe of surface hydrophilicity 
J. Song, B. Allison, S. Han, MRS Bull., 39 (12) (2014) 1082-1088
DOI: 10.1557/mrs.2014.254

Cholesterol Enhances Surface Water Diffusion of Phospholipid Bilayers
C. Y. Cheng, L. Olijve, R. Kausik, S. Han, J. Chem. Phys., 141 (22D513) (2014)
PMID: 25494784; PMCID: PMC4201661
DOI: 10.1063/1.4897539

Determining the oligomeric structure of proteorhodopsin by Gd3+-based pulsed dipolar spectroscopy of multiple distances
D.T. Edwards, T. Huber, S. Hussain, K.M. Stone, M. Kinnebrew, I. Kaminker, E. Matalon, M.S. Sherwin, D. Goldfarb, S. Han, Structure, 22 (11) (2014) 1677-1686
DOI: 10.1016/j.str.2014.09.008 PMID: 25438671.

Intrinsic Surface-Drying Properties of Bioadhesive Proteins
Y. Akdogan, W. Wei, K. Huang, Y. Kageyama, E. W. Danner, D. R. Miller, N. R. Martinez Rodriguez, J. H. Waite, S. Han, Angew. Chem., 126 (42) (2014) 11435-11438
PMID: 25168789; PMCID: PMC4198389
DOI: 10.1002/ange.201406858  

Featured in Nature Materials | Research Highlights

Role of Electron Spin Dynamics on Solid-State Dynamic Nuclear Polarization Performance
T. Siaw, M. Fehr, A. Lund, A. Latimer, S. Walker D. Edwards, S. Han, Phys. Chem. Chem. Phys., 16 (2014) 18694-18706.
DOI: 10.1039/C4CP02013H PMID: 24968276.

Probing water density and dynamics in the chaperonin GroEL cavity
J. Franck, M. Sokolovski, N. Kessler, E. Matalon, M. Gordon-Grossman, S. Han, D. Goldfarb, A. Horovitz, J. Am. Chem. Soc., 136 (26) (2014) 9396-9403
PMID: 24888581; PMCID: PMC4091268
DOI: 10.1021/ja503501x  

Specific Ions Modulate Diffusion Dynamics of Hydration Water on Lipid Membrane Surfaces
J. Song, J. Franck, P. Pincus, M.W. Kim, S. Han, J. Am. Chem. Soc., 136 (6) (2014) 2642-2649
PMID: 24456096; PMCID: PMC3985948
DOI: 10.1021/ja4121692   013 Journal Articles

Fluidity and Water in Nanoscale Domains Define Coacervate Hydrogels
J.H. Ortony, S.H. Choi, J.M. Spruell, J.N. Hunt, N.A. Lynd, D.V. Krogstad, V.S. Urban, C.J. Hawker, E.J. Kramer, S. Han, Chemical Sciences 5 (2013) 58-67
DOI: 10.1039/C3SC52368C

Hydration Dynamics as an Intrinsic Ruler for Refining Protein Structure at Lipid Membrane Interfaces
C.Y. Cheng, J. Varkey, M.R. Ambroso, R. Langen, S. Han, Proc. Natl. Acad. Sci. 110 (42) (2013) 16838–16843
PMID: 24082088; PMCID: PMC3800990
DOI: 10.1073/pnas.1307678110  

DAC-board based X-band EPR Spectrometer with Arbitrary Waveform Control (w/Audio Slide Presentation)
T. Kaufmann, T.J. Keller, J.M. Franck, R.P. Barnes, S.J. Glaser, J.M. Martinis, S. Han, J. Magn. Reson. 235 (2013) 95-108
PMID: 23999530; PMCID: PMC3863685
DOI: 10.1016/j.jmr.2013.07.015  

Quantitative cw Overhauser Dynamic Nuclear Polarization for the Analysis of Local Water Dynamics
J. M. Franck, A. Pavlova, J.A. Scott, S. Han, Prog. Nucl. Magn. Reson. 74 (2013) 33-56
PMID: 24083461; PMCID: PMC3798041
DOI: 10.1016/j.pnmrs.2013.06.001  

Temperature Dependence of High Field 13C Dynamic Nuclear Polarization Processes below 35 Kelvin
S.A. Walker, D.T. Edwards, T. Siaw, B.D. Armstrong, S. Han, Phys. Chem. Chem. Phys. 15 (36) (2013) 15106-15120
DOI:10.1039/C3CP51628H PMID: 23925724.

Extending the Distance Range Accessed with Continuous Wave EPR with Gd3+ Spin Probes at High Magnetic Fields
D.T. Edwards, Z. Ma, T.J. Meade, D. Goldfarb, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 15 (2013) 11313-11326
PMID: 23732863; PMCID: PMC4142211
DOI: 10.1039/C3CP43787F  

Overhauser Dynamic Nuclear Polarization-Enhanced NMR Relaxometry
J.M. Franck, R. Kausik, S. Han, Microporous and Mesoporous Materials, 178 (2013) 113-118
PMID: 23837010; PMCID: PMC3702190
DOI: 10.1016/j.micromeso.2013.04.019  

Asymmetric Collapse in Biomimetic Complex Coacervates Revealed by Local Polymer and Water Dynamics
J.H. Ortony, D.S. Hwang, J.M. Franck, J.H. Waite, S. Han, Biomacromolecules, 14(5) (2013) 1395-1402
PMID: 23540713; PMCID: PMC4090114
DOI: 10.1021/bm4000579

Phase Cycling with a 240 GHz Free Electron Laser-powered Electron Paramagnetic Resonance Spectrometer
D.T. Edwards, Y. Zhang, S.J. Glaser, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 15 (2013) 5707-5719
DOI: 10.1039/C3CP44492A PMID: 23474874.
Nonlinear Scaling of Surface Water Diffusion with Bulk Water Viscosity of Crowded Solutions
J.M. Franck, J.A. Scott, S. Han, J. Am. Chem. Soc., 135(11) (2013) 4175-4178
DOI: 10.1021/ja3112912 PMID: 23347324; PMCID: PMC3785640.

Structural Insight into Proteorhodopsin Oligomers
K. M. Stone, J. Voska, M. Kinnebrew, A. Pavlova, M. J. N. Junk, S. Han, Biophys. J., 104(2) (2013) 472-481
PMID: 23442869; PMCID: PMC3552253
DOI: 10.1016/j.bpj.2012.11.3831  

Dynamic Nuclear Polarization Methods in Solids and Solutions to Explore Membrane Proteins and Membrane Systems
C.Y. Cheng and S. Han, Annu. Rev. Phys. Chem., 64 (2013) 507-532
DOI: 10.1146/annurev-physchem-040412-110028 PMID: 23331309.
Transmembrane Protein Activation Refined by Site-Specific Hydration Dynamics
S. Hussain, J. M. Franck, S. Han, Angew. Chem. Int. Ed., 52(7) (2013) 1953 - 1958
DOI: 10.1002/anie.201206147 PMID: 23307344

2013 Book Chapters

Annual Review of Physical Chemistry
Vol. 64, Annual Reviews (2013)

Dynamic Nuclear Polarization Methods in Solids and Solutions to Explore Membrane Proteins and Membrane Systems
C. Cheng and S. Han
PMID: 23331309
DOI: 10.1146/annurev-physchem-040412-110028

2012 Journal Articles

Quantitative Analysis of Molecular Transport across Liposomal Bilayer by J-mediated 13C Dynamic Nuclear Polarization
C.Y. Cheng, J.G.M.O. Goor, S. Han, Anal. Chem., 84(21) (2012) 8936-3940
DOI: 10.1021/ac301932h PMID: 23072518; PMC4656247.
Nature of Interactions between PEO-PPO-PEO Triblock Copolymers and Lipid Membranes: The Role of Hydration Dynamics Revealed by Dynamic Nuclear Polarization
C. Cheng, J. Wang, R. Kausik, K. C. Lee, S. Han, Biomacromolecules, 13(9) (2012) 2624-2633
DOI: 10.1021/bm300848c PubMed PMID: 22808941.
Distance measurements across randomly distributed nitroxide probes from the temperature dependence of the electron spin phase memory time at 240 GHz
D.T. Edwards, S. Takahashi, M. S. Sherwin, S. Han, J. Magn. Reson., 223 (2012) 198-206
DOI: 10.1016/j.jmr.2012.07.004 PubMed PMID: 22975249.
Inductively coupled NMR probe for versatile dynamic nuclear polarization operation at 7 Tesla: observation of 61 ± 2% 1H polarization at 4 K
T. Siaw, S. A. Walker, B. D. Armstrong, S. Han, J. Magn. Reson., 221 (2012) 5-10
DOI: 10.1016/j.jmr.2012.05.017 PubMed PMID: 22743536.
Hyperpolarized Water as an MRI Contrast Agent
M. D. Lingwood, T. Siaw, N. Sailasuta, O. A. Abulseoud, H. R. Chan, B. D. Ross, P. Bhattacharya, S. Han, , Radiology, 265 (3) (2012) 418-425
DOI:  PMID: 22996746; PMCID: PMC3480810.
Pulsed electron paramagnetic resonance spectroscopy powered by a free-electron laser
S. Takahashi, L.-C. Brunel, D. T. Edwards, J. van Tol, G. Ramian, S. Han, M. S. Sherwin, Nature 489 (74160) (2012) 409-13
DOI: 10.1038/nature11437 PMID: 22996555.
Overhauser dynamic nuclear polarization amplification of NMR flow imaging
M. D. Lingwood, A. J. Sederman, M. D. Mantle, L. F. Gladden, S. Han, J. Magn. Reson. 216 (2012) 94–100
DOI: 10.1016/j.jmr.2012.01.007
An ultrasensitive tool exploiting hydration dynamics to decipher weak lipid membrane–polymer interactions
C. Cheng, J. Wang, R. Kausik, K. C. Lee, S. Han, J. Magn. Reson. 215 (2012) 115-119
DOI: 10.1016/j.jmr.2011.12.004 PMID: 22230738.

2011 Journal Articles

Site-Specific Hydration Dynamics in the Nonpolar Core of a Molten Globule by Dynamic Nuclear Polarization of Water
B.D. Armstrong, J. Choi, C. Lopez, D. A. Wesener, W. Hubbell, S. Cavagnero, S. Han, J. Am. Chem. Soc.133 (2011) 5987–5995
PMID: 21443207; PMCID: PMC3095581
DOI: 10.1021/ja111515s

Dynamics and State of Lipid Bilayer-internal Water Unraveled with Solution State 1H Dynamic Nuclear Polarization
R. Kausik, S. Han, Phys. Chem. Chem. Phys. (2011) 13, 7732-7746
DOI: 10.1039/c0cp02512g PMID: 21423982.
Probing the Hydration Water Diffusion of Macromolecular Surfaces and Interfaces
J. H. Ortony, C.-Y. Cheng, R. Kausik, A. Pavlova, J. Hunt, S. Han, New J. Phys.13 (2011) 015006 (15pp)
DOI: 10.1088/1367-2630/13/1/015006

2011 Book Chapters

Annual Reports on NMR Spectroscopy
Edited by: Graham A. Webb

Vol. 73, Elsevier Academic Press (2011)

Solution State Dynamics Nuclear Polarization 
M. D. Lingwood, S. Han. (Pages 83-126)
PMID: 12137529

2010 Journal Articles

A 200 GHz Dynamic Nuclear Polarization Spectrometer
B.D. Armstrong, D.T. Edwards, R.J. Wylde, S.A. Walker, S. Han, Phys. Chem. Chem. Phys., 12 (2010) 5920-5926
DOI: 10.1039/c002290j PMID: 20461268.
Continuous Flow Overhauser Dynamic Nuclear Polarization of Water in the Fringe Field of a Clinical Magnetic Resonance Imaging System for Authentic Image Contrast
M. D. Lingwood, T. A. Siaw, N. Sailasuta, B. D. Ross, P. Bhattacharya and S. Han, J. Magn. Reson. 205 (2) (2010) 247-254
DOI: 10.1016/j.jmr.2010.05.008 PMID: 20541445; PMCID: PMC4724375.
Heisenberg Spin Exchange Effects of Nitroxide Radicals on Overhauser Dynamic Nuclear Polarization in the Low Field Limit at 1.5 mT
M.D. Lingwood, I.A. Ivanov, A.R. Cote, S. Han, J. Magn. Reson. 204 (1) (2010) 56-63
DOI: 10.1016/j.jmr.2010.01.015 PMID: 20188611.
L-band Overhauser dynamic nuclear polarization
S. Garcia, J.H. Walton, B.A. Armstrong, S. Han, M.J. Mcarthy, J. Magn. Reson. 203 (1) (2010) 138-143
DOI: 10.1016/j.jmr.2009.12.012 PMID: 20045658.

2009 Journal Articles

Ultrasensitive Detection of Interfacial Water Diffusion on Lipid Vesicle Surfaces at Molecular Length Scales
R. Kausik, S. Han.
J. Am. Chem. Soc. 131 (51) (2009) 18254-18256
DOI: 10.1021/ja9060849 PMID: 19791740.
Dynamic Nuclear Polarization of 13C in Aqueous Solutions under Ambient Conditions
M.D. Lingwood, S. Han, J. Magn. Reson. 201 (2) (2009) 137-145
DOI: 10.1016/j.jmr.2009.09.002 PMID: 19783462.

Local Water Dynamics in Coacervated Polyelectrolytes Monitored through Dynamic Nuclear Polarization-Enhanced 1H NMR
R. Kausik, A. Srivastava, P.A. Korevaar, G. Stucky, J.H. Waite, S. Han, Macromolecules 42 (19) (2009) 7404–7412
PMID: 20814445; PMCID: PMC2929756
DOI: 10.1021/ma901137g  

Site-specific Dynamic Nuclear Polarization of Hydration Water as a Generally Applicable Approach to Monitor Protein Aggregation
A. Pavlova, E.R. McCarney, D.W. Peterson, F.W. Dahlquist, J. Lew, S. Han, Phys. Chem. Chem. Phys. (PCCP) 11 (2009) 6833-6839
PMID: 19639158; PMCID: PMC3153360
DOI: 10.1039/b906101k  

Overhauser Dynamic Nuclear Polarization and Molecular Dynamics Simulations using Pyrroline and Piperidine Ring Nitroxide Radicals
B.D. Armstrong, P. Soto, J. Shea, S. Han, J. Magn. Reson. 200 (2009) 137-141
DOI: 10.1016/j.jmr.2009.05.013 PMID: 19535275.
Overhauser Dynamic Nuclear Polarization To Study Local Water Dynamics
B.D. Armstrong, S. Han, J. Am. Chem. Soc. 131 (13) (2009) 4641-4647
DOI: 10.1021/ja809259q PMID: 19290661.
Study of Local Diffusion Coefficients of the Hydration Layer of Lipid Vesicle Bilayers
R. Kausik, B. D. Armstrong, S. Han, Diffusion Fundamentals 10 (2009) 27.1-27.4
PMCID: PMC3985948
DOI: 10.1021/ja4121692

 

2008 Journal Articles

Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance and Electron Spin Resonance Studies of Hydration and Local Water Dynamics in Micelle and Vesicle Assemblies
E. R. McCarney, B.D. Armstrong, R. Kausik, S. Han, Langmuir. 24 (18) (2008) 10062-10072
DOI: 10.1021/la800334k PMID: 18700788.
Dynamic Nuclear Polarization Studies of Local Water Dynamics in Soft Molecular Assemblies at 9.8 GHz
S. Han, E. R. McCarney, B.D. Armstrong, Appl. Magn. Reson. 34 (3-4) (2008) 439-451
DOI: 10.1007/s00723-008-0135-3
Portable X-Band System for Solution State Dynamic Nuclear Polarization
B.D. Armstrong, M.D. Lingwood, E.R. McCarney, E.R. Brown, P. Blümler, S. Han, J. Magn. Reson. 191 (2) (2008) 273-281
DOI: 10.1016/j.jmr.2008.01.004 PMID:18226943.
Spin-Labeled Gel for the Production of Radical-Free Dynamic Nuclear Polarization Enhanced Molecules for NMR Spectroscopy and Imaging
E.R. McCarney, S. Han, J. Magn. Reson. 190 (2) (2008) 307-315
DOI: 10.1016/j.jmr.2007.11.013
Local Hydration Dynamics in Soft Matter by Dynamic Nuclear Polarization of 1H-water
B. D. Armstrong, R. Kausik, S. Han, AIP Conf. Proc. 1081 (2008) 14-17
DOI: 10.1063/1.3058535

2008 Book Chapters

Magnetic Resonance Microscopy
Edited by: S. Codd, J. Seymour
Wiley-VCH, Weinheim, Germany

Dynamic Nuclear Polarization-Enhanced Magnetic Resonance Analysis at X-band using Amplified 1H Water Signal
S. Han., E.R. McCarney, B.D. Armstrong and M.D. Lingwood (Chapter 11)
DOI:10.1002/9783527626052.ch11

Archived Publications