former graduate students
former undergraduate researchers
former postdocs and visiting scholars

rdl R. Daniel Little      little@chem.ucsb.edu
B.S., chemistry and mathematics, University of Wisconsin at Superior
Ph.D. University of Wisconsin
Postdoctoral fellow, Yale University
A.P. Sloan Fellow
UCSB Plous Award recipient


Graduate Researchers

Jennifer Mallory Jennifer Mallory      jmallory@chem.ucsb.edu
B.S. Chemistry, Cal Poly San Luis Obispo

My current research efforts focus on trying to enhance the diastereoselectivity of the electroreductive cyclization reaction (ERC).  The use of sacrificial anodes and metal additives is also being explored.  In addition, chiral auxiliaries are under investigation to control absolute stereochemistry.  The results will be showcased in the synthesis of a natural product by using the ERC reaction to construct a bond in the key step of the synthesis.
   
Elizabeth Flynn Elizabeth Flynn      eflynnn@chem.ucsb.edu

   
Abdul Hackim
Abdul Hackim       ahackim@chem.ucsb.edu
B.S. Oregon State University

The focus of my research is upon the synthesis of simplified structural analogues of the pseudopterosins. The goal of this project is to gain a better understanding of their structure activity relationship profile.

I am also working on the total synthesis of (-)-diplopyrone and am studying the role of stereoelectronic effects upon redox properties of organic substrates.  This work requires the development of expertise in synthesis, electrochemistry, and the use of various quantum calculation tools.




Jinnie Myung Jinnie Myung      jmyung@chem.ucsb.edu
B.S. Binghamton University-SUNY

My current research focuses upon the generation and use of alkylidene carbenes and their intramolecular addition to a pendant alkene, leading to the formation of TMM diyls under very mild conditions.  Subsequent and sequential intramolecular cycloaddition has been shown to lead cleanly to several different ring systems, including the linearly fused tricyclopentanoid skeleton that is common to a host of bioactive natural products.
 Randi Gbur  Randi Gbur     University of Texas at Arlington


Joon
Seung Joon Yoo (Joon)  UCSB


Undergraduate Researchers






Ian Pahk
Ian Pahk

Ian Pahk
     
At the present time I am synthesizing several housanes, that is, moleculas possessing the bicyclo[2.1.0] core framework.  Some of these systems display broad, ill-defined cyclic voltammograms.  A series of variable temperature CV experiments will be carried out in an effort to determine the origin of the featureless curves.  We susp[ect that they are associated with the existence of dynamic influences that we hope to "freeze out" as the temperature is lowered.  This research promises to provide insight into the role of stereoelectronic effects in determining the ease of oxidation or reduction of a substrate. 


Joaquin Gutierrez


Joaquin Gutierrez - from UNAM in Mexico City


 



Postdoctoral Scholar

 
Dr. Wei Zhong
Dr. Wei Zhong

postdoctoral scholar to join the group October 1, 2007;    University of Georgia - Complex Carbohydrate Research Institute

Dr. Zhong's research focuses primarily upon the chemistry and pharmacology of the pseudopterosin class of marine natural products.  The research combines natural product characterization, synthesis, degradation, total synthesis, as well as a detailed investigation into what makes these molecules work.

Another area of investigation focuses upon a total synthesis of the anti-tumor agent, aphidicolin.  The synthetic approach is to captilize upon sequential intramolecular diyl trapping and Diels-Alder reactions.





We can be reached at (805)893-3953 or little@chem.ucsb.edu