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 Asher
Lower
E-Mail: alower@chem.ucsb.edu
x7694; Rm. 2211
Education
1999 Internship with M. Wright. Virginia Commonwealth University, Richmond,
VA.
2000 Internship with L. Tolbert. Georgia Institute of Technology, Atlanta,
GA.
2000-2001 Undergraduate research with D. Ball. CSU, Chico; All
E-Retanoic Acid Synthesis.
1997-2001 BS Professional Chemistry, Honors. California State University,
Chico, CA.
2001- Graduate work in organic synthesis and methodology in the Lipshutz
group.
Current Research/Publications
Ligand Accelerated Asymmetric Hydrosilylation of Heteroaromatic Ketones
Using CuH Catalyst. Ongoing work involves using novel chiral ligands to
effect asymmetric reduction of ketones associated with known drug intermediates
in high enantiomeric excess.
"Copper(I)
Hydride-Catalyzed Asymmetric Hydrosilylation of Heteroaromatic Ketones",
B.H. Lipshutz, A. Lower, K. Noson, Org. Lett. 2002, 23,
4045-4048.
"Asymmetric
Hydrosilylation of Aryl Ketones Catalyzed by Copper Hydride Complexed
by Nonracemic Biphenyl Bis-Phosphine Ligands", B. H. Lipshutz, K.
Noson, W. Crisman, A. Lower, J. Am. Chem. Soc., 2003, 125,
8779-8789.
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