Chem 142A
Biochemistry
Fall 2007
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Chem 142A Fall 2007 |
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Dr. Kalju Kahn
Office: PSB-N 2623
Office hours: Tue and Thu 11:00-12:00 PM or by appointment
Phone: (805) 893-6157
E-mail: kalju@chem.ucsb.edu
Website:www.chem.ucsb.edu/~kalju/
Nicholas Fera
Office: CHEM 1432
Office hours: M,W 11:30-12:30 in Chem 1005C (the chem reading room) or by appointment
Phone: (805) 893-8283
E-mail: Fera@lifesci.ucsb.edu
Lecture: MWR 1:00-1:50 Place: GIRV 1004 (Nice!)
Chem 142A is the first course of a three-course sequence (Chem 142ABC) and serves as an introduction and prerequisite for the two following courses. The Chem 142 sequence provides the students fundamentals of biochemistry and molecular biology, and is mainly intended for students in the field of chemistry and biology.
The current course, Chem 142A, has two main focuses:
| Syllabus | General information about the course. | |
| Textbook | Lehninger Principles of Biochemistry (Nelson & Cox) | Link |
| Last Year | Biochemistry Chem 142A: Summer 2006 | Link |
| Exam | Midterm I Preparation Guide | |
| Exam | Midterm I Practice Problems | |
| Exam | Midterm I Answer Key (Fall 2007) | |
| Exam | Midterm II Preparation Guide | |
| Exam | Midterm II Answer Key (Fall 2007) | |
| Exam | Practice Problem-Solving Questions | Link |
| Exam | Final Preparation Guide | |
| Exam | Final Preparation: Suggested Textbook Problems | |
| Exam | Final Preparation: Sample Questions from 2003 | |
| Exam | Final Preparation: Selected Answers from the 2006 Final | |
| Exam | Final Exam Key: Fall 2007 | |
| Exam | Statistics Page | Link |
On days that I use PowerPoint slides in the class, the notes will be posted here before 7:00 a.m. of that day.
| Notes | Powerpoint Lecture Note Pages in PDF | Acrobat |
| Sept 28 | Foundations of Biochemistry: The Molecular Logic of Life (Free Access) | |
| Oct 1-Oct 3 | Foundations of Biochemistry: Cells and Evolution | |
| Oct 5 | Foundations of Biochemistry: Chemical Principles | |
| Oct 8 | Foundations of Biochemistry: Forces and Water | |
| Oct 10 | Ionization of Water, pH, pKa, Buffers | |
| Oct 12 | Amino Acids | |
| Oct 15 | Peptides and Proteins: Intro to Structure and Methods | |
| Oct 22 | Proteins: Secondary Structure | |
| Oct 22 | Fibrous Proteins: Structure and Function | |
| Oct 24 | Membraneous and Globular Proteins. Protein Folding | |
| Oct 26 | Function of Globular Proteins. Hemoglobin | |
| Oct 29 | Immune System and Antibodies. Motor Proteins. | |
| Oct 31 | Enzyme Catalysis | |
| Nov 2-5 | Enzyme Kinetics and Inhibition | |
| Nov 5-7 | Carbohydrates | |
| Nov 16 | Glycobiology | |
| Nov 19 | Nucleotides and Nucleic Acids | |
| Nov 19 - Nov 21 | DNA Structure and Function | |
| Nov 26 | DNA Technologies | |
| Nov 28 | Lipids | |
| Dec 3-5 | Membrane Biochemistry | |
| Dec 7 | Introduction to Biosignaling | |
| Dec 13 | Final Exam |
The assignments are posted one week before the due date. Answers shall be turned in no later than by the end of the lecture on Friday of a week the homework is due.
| Assignments | PDF files | Acrobat |
| 1 | Foundations of Biochemistry (Due Oct 5th) | |
| 2 | Evolution and Chemical Basis of Life (Due Oct 12) | |
| 3 | Properties and Separation of Peptides (Due Oct 29) | |
| 4 | Thermodynamics of Biomolecular Interactions (Due Nov 5) | |
| 5 | Nucleic Acids and DNA Technologies (Due Nov 30) | |
| Extra | Dynamical Contribution to Catalysis (find one error: 10 pts, Due Dec 5) |
| Assignments | PDF files | Acrobat |
| 1 | Foundations of Biochemistry | |
| 2 | Evolution and Chemical Basis of Life | No PDF |
| 3 | Properties and Separation of Peptides | |
| 4 | Thermodynamics of Biomolecular Interactions | |
| 5 | Nucleic Acids and DNA Technologies | |
| Extra | Dynamical Contribution to Catalysis |
Protein Data Bank
How to Create Movies with PyMOL
PyMOL Molecular Visualization Program
Biomolecular Visualization Examples with PyMol
Induced Fit in Hexokinase: Animations
Chemscape Chime to view 3D structures online
How To View Stereo Pair Photographs
Stereo Viewing
Hints for studying biochemistry
Membrane Biochemistry Resources at UCSB
Induced Fit Animations
Fall 2002 by Dr. Shea
Fall 2001 by Dr. Gerig
Introductory Biochemistry at Pennsylvania State University
Electronic Journals
Spectroscopy Online Resources
UCSB General Catalog
UCSB Campus Map
UCSB Gold Login
UCSB Umail Access
UCSB Environmental Health and Safety