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Selected Publications

Bode Group Publications

  • Chiang, P.-C.; Kaeobamrung, J.; Bode, J. W. "Enantioselective, Cyclopentene-Forming Annulations via NHC-Catalyzed Benzoin–Oxy-Cope Reactions", J. Am. Chem. Soc. 2007, 129, 3520–3521. Link

  • He, M.; Uc, G. J.; Bode, J. W. "Chiral, N-Heterocyclic Carbene Catalyzed Oxodiene Diels-Alder Reactions with Low Catalyst Loadings", J. Am. Chem. Soc. 2006, 128, 15088–15089. Link

  • Bode, J. W. "Emerging Methods for the Synthesis of Amide and Peptide Bonds", Curr. Opin. Drug Disc. Dev. 2006, 9, 765–775 .

  • Lippert, A. R.; Kaeobamrung, J.; Bode, J. W. "Synthesis of Oligosubstituted Bullvalones: Shapeshifiting Molecules Under Basic Conditions ", J. Am. Chem. Soc. 2006, 128, 14738–14739. Link

  • Sohn, S. S.; Bode, J. W. "N-Heterocyclic Carbene Catalyzed C–C Bond Cleavage in Redox Esterifications of Chiral Formylcyclopropanes", Angew. Chem. Int. Ed. 2006, 6021–6024. Link

  • He, M.; Struble, J. R.; Bode, J. W. "Highly Enantioselective Azadiene Diels-Alder Reactions Catalyzed by Chiral N-Heterocyclic Carbenes", J. Am. Chem. Soc. 2006, 8148–8150. Link

  • Carrillo, N.; Davalos, E. A.; Russak, J. A.; Bode, J. W. "Iterative, Aqueous Synthesis of b3-oligopeptides without Coupling Reagents ", J. Am. Chem. Soc. 2006, 128, 1452-1453. Link C&E News

  • Bode, J. W.; Fox, R. M.; Baucom, K. D. "Decarboxylative Condensations of alpha-Ketoacids and N-Alkylhydroxylamines: A New Amide Ligation Reaction", Angew. Chem. Int. Ed.2006, 45, 1248-1252. Link C&E News

  • Sohn, S.; Bode, J. W. "Catalytic Generation of Activated Carboxylates from Enals: A Product Determining Role for the Base ", Org. Lett. 2005, 7, 3873-3876. Link Org-chem.org Angew. Highlight

  • He, M.; Bode, J. W. "Catalytic Synthesis of gamma-Lactams via Direct Annulations of Enals and N-Sulfonylimines", Org. Lett. 2005, 7, 3131–3134. Link Angew. Highlight


  • Sohn, S. S.; Rosen, E. L.; Bode, J. W. "N-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: gamma-Butyrolactones by Direct Annulations of Enals and Aldehydes", J. Am. Chem. Soc. 2004, 126, 14370-14371. Link Angew. Highlight


  • Chow, K. Y.-K.; Bode, J. W. "Catalytic Generation of Activated Carboxylates: Direct, Stereoselective Synthesis of beta-Hydroxyesters from Epoxyaldehydes" J. Am. Chem. Soc. 2004, 126, 8126-8127. Link Angew. Highlight

Undergraduate, Graduate, and Postdoctoral Publications

  • Takikawa, H.; Hachisu, Y.; Bode, J. W.; Suzuki, K. " Catalytic, Enantioselective Crossed Aldehyde–Ketone Benzoin Cyclizations”, Angew. Chem. Int. Ed. 2006, 45, 3492–3494. LInk
  • Hachisu, Y.; Bode, J. W.; Suzuki, K. "Thiazolium Ylide Catalyzed Intramolecular Aldehyde--Ketone Benzoin-Forming Reactions: Substrate Scope" Adv. Syn. Cat. 2004, 1097–1100. LInk
  • Matsuura, T.; Bode, J. W.; Hachisu, Y.; Suzuki, K. "Molecular Sieve (MS 4A) Promoted Cyclocondensation of Hindered, Aromatic Nitrile Oxides and Cyclic Diketones under Mild Conditions", Synlett 2003, 1746-1748. Link
  • Hachisu, Y.; Bode, J. W.; Suzuki, K. "Catalytic Intramolecular Aldehyde-Ketone Benzoin Reactions: A Novel Synthesis of Functionalized Preanthraquinones", J. Am. Chem. Soc. 2003, 125, 8432-8433. Link
  • Bode, J. W.; Hachisu, Y.; Matsuura, T.; Suzuki, K. Amine-Promoted Cyclocondensation of Highly Substituted Aromatic Nitrile Oxides with Diketones", Tetrahedron Lett. 2003, 44, 3555-3558. Link
  • Bode, J.W.; Suzuki K. "Structural Incongruities of Coleophomone Natural Products: Insights by Total Synthesis of a Semi-Synthetic Derivative" Tetrahedron Lett. 2003, 44, in 3559-3563. Link
  • Bode, J.W.; Hachisu, Y.; Matsuura, T.; Suzuki, K. "Facile Construction and Divergent Transformation of Polycyclic Isoxazoles: Direct Access to Polyketide Architectures", Org. Lett. 2003, 5, 391-394. Link
  • Bode, J. W.; Uekusa, H.; Suzuki, K. "Rearrangement Promoted Cascade Reactions for the Stereoselective Synthesis of Highly Functionalized Polycycles", Org. Lett. 2003, 5, 395-398. Link
  • Bode, J. W.; Gauthier, D. R.; Carreira, E. M. "Facile Enantioselective Synthesis of a Key Homoallylic Alcohol Building Block for Polyketide Synthesis: TiF4-BINOL Catalyzed Allylsilylation", J. Chem. Soc. Chem. Comm. 2001, 2560-2561. Link
  • Bode, J. W.; Carreira, E. M. "Stereoselective Syntheses of Epothilones A and B via Nitrile Oxide Cycloadditions and Related Studies", J. Org. Chem. 2001, 64, 6410-6424. Link
  • Bode, J. W.; Carreira, E. M. "A Mild and Chemoselective Method for the Reduction of Conjugated Isoxazolines to Beta-Hydroxy Ketones", Org. Lett. 2001, 3, 1587-1590. Link
  • Bode, J. W.; Fraefel, N.; Muri, D.; Carreira, E. M. "A General Solution to the Modular Synthesis of Polyketide Building Blocks via Kanemasa Hydroxyl-Directed Nitrile Oxide Cycloadditions", Angew. Chem. Int. Ed. 2001, 40, 2082-2085. Link
  • Bode, J. W.; Carreira, E. M. "Stereoselective Syntheses of Epothilones A and B via Hydroxyl Directed Nitrile Oxide Cycloadditions", J. Am. Chem. Soc. 2001, 123, 3611-3612. Link
  • Muri, D.; Bode, J.W.; Carreira, E.M. "A Novel, General Method for the Synthesis of Nitrile Oxides: Dehydration of O-Silylated Hydroxamic Acids", Organic Lett. 2000, 2, 539-541. Link
  • Bode, J. W.; Doyle, M. P.; Protopopova, M. N. Zhou, Q-L. "Intramolecular Regioselective Insertion into Unactivated Carbon-Hydrogen Bonds with Diazoacetates of Primary Alcohols Catalyzed by Chiral Dirhodium(II) Carboxamidates. Highly Enantioselective Total Synthesis of Natural Lignan Lactones." J. Org. Chem. 1996, 61, 9146-9155. Link
  • Doyle, M.P.; Protopopova, M.N. Zhou, Q.-L.; Bode, J.W.; Simonsen, S.H.; Lynch, V. "Optimization of Enantiocontrol for Carbon-Hydrogen Insertion with Chiral Dirhodium(II) Carboxamidates. Synthesis of Natural Dibenzylbutyrolactone Lignans from 3-Aryl-1-Propyl Diazoacetates in High Optical Purity." J. Org. Chem. 1995, 60, 6654-6655. Link

Book Chapters

  • Bode, J. W.; Carreira, E. M. "Total Synthesis of Macrolides" in The Chemical Synthesis of Natural Products; Hale, K. J., Ed.; Sheffield Academic Press: Sheffield, 2000; pp 40-63.

Scientific Patents

  • Bode, J.W.; Suzuki, K. "Polycyclic Compounds and a Method for their Manufacture", Japanese Patent Filed.
  • Bode, J. W.; Suzuki, K. "Preparation of 3-phenyl-5,6,7,8-tetrahydrobenz[d]isoxazol-5-one derivatives and a process for producing the same": WO2003076419.