Biological Hydration Water Publications

2019 Book Chapter

Methods in Enzymology: Biological NMR Part B
Vol. 615, Elsevier Inc. (2019)

Chapter Five - Overhauser Dynamic Nuclear Polarization for the Study of Hydration Dynamics, Explained
J. M. Franck and S. Han
DOI: 10.1016/bs.mie.2018.09.024

2019 Journal Articles

Anomalous solute diffusivity in ionic liquids: Label-free visualization and physical origins
A. V. Bayles, C. S. Valentine, T. Überrück, S. P. O. Danielsen, S. Han, M. E. Helgeson, T. M. Squires. Phys. Rev. X (2018).

2018 Journal Articles

Effect of nitroxide spin probes on the transport properties of Nafion membranes
T. Überrück, O. Neudert, K.-D. Kreuer, B. Blümich, J. Granwehr, S. Stapf, S. Han. Phys. Chem. Chem. Phys., 20 (2018), 26660-26674.
DOI: 10.1039/C8CP04607G
Heterogeneity of network structure and water dynamics in κ-carrageenan gels probed by nanoparticle diffusometry
D. de Kort, E. Schuster, F. Hoeben, R. Barnes, M. Emondts, H. Janssen, N. Lorén, S. Han, H. van As, J. van Duynhoven.  Langmuir, 34 (37) (2018), 11110-11120.
DOI: 10.1021/acs.langmuir.8b01052

2017 Journal Articles

Spatially Heterogeneous Surface Water Diffusivity around Structured Protein Surfaces at Equilibrium
R. Barnes, S. Sun, Y. Fichou, F.W. Dahlquist, M. Heyden, S. Han, J. Am. Chem. Soc., 139 (49) (2017) 17890-17901.
DOI:10.1021/jacs.7b08606 Highlighted Cover Article:
Simple peptide coacervates adapted for rapid pressure-sensitive wet adhesion
I. Kaminker, W. Wei, A.M. Schrader, Y. Talmon, M.T. Valentine, J.N. Israelachvili, J.H. Waite, S. Han, Soft Matter., 13 (48) (2017) 9122-9131.
Water Dynamics from the Surface to the Interior of a Supramolecular Nanostructure
J.H. Ortony, B. Qiao, C.J. Newcomb, T.J. Keller, L.C. Palmer, E. Deiss-Yehiely, M.O. Cruz S. Han, S.I. Stupp, J. Am. Chem. Soc., 139 (26) (2017) 8915–8921
DOI:10.1021/jacs.7b02969 Highlighted in Nature Chemistry News and Views:
Molecular and structural basis of low interfacial energy of complex coacervates in water
Y. Jho, H. Yoo, Y. Lin, S. Han, D. Hwang, Adv. Colloid Interface Sci., 239 (2017) 61–73
DOI:10.1016/j.cis.2016.07.003. PMID: 27499328.

2016 Journal Articles

Hydration dynamics of a peripheral membrane protein
O. Fisette, C. Paslack, R. Barnes, J.M. Isas, R. Langen, M. Heyden, S. Han, L.V. Schafer, J. Am Chem. Soc., 138 (2016) 11526-11535
Contrasting Effects of Glycerol and DMSO on Lipid Membrane Surface Hydration Dynamics and Forces
A. Schrader, C. Cheng, J. Israelachvili, S. Han, J. Chem. Phys., 145 (2016) 041101
Stability of protein-specific hydration shell on crowding
K. Huang, C.N. Kingsley, R. Sheil, C. Cheng, J.B. Bierma, K.W. Roskamp, D. Khago, R.W. Martin, S. Han, J. Am. Chem. Soc., 138 (16) (2016) 5392–5402

2015 Journal Articles

Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?
P. Stals, C. Cheng, L. Beek, A. Wauters, A. Palmans, S. Han, E. Meijer, Chem. Sci., 7 (2015) 2011-2015
DOI: 10.1039/C5SC02319J
Anomalously rapid hydration water diffusion dynamics near DNA surfaces
J. Franck, Y. Ding, K. Stone, P. Qin, S. Han, J. Am. Chem. Soc., 137 (37) (2015) 12013-12023
PMCID: PMC4656248
DOI: 10.1021/jacs.5b05813
Correlating steric-hydration forces with water dynamics through surface force and diffusion NMR measurements in a lipid-DMSO-H2O system
A. Schrader, S. Donaldson, J. Song, C. Cheng, D. Lee, S. Han, J. Israelachvili, Proc. Natl. Acad. Sci., 112 (34) (2015) 10708–10713
PMCID: PMC4553805
DOI: 10.1073/pnas.1512325112
DMSO induces dehydration near lipid membrane surfaces
C. Cheng, J. Song, J. Pas, L. Meijer, S. Han, Biophys. J., 109 (2) (2015) 330-339
PMCID: PMC4621616
DOI: 10.1016/j.bpj.2015.06.011
Ion specific effects: decoupling ion-ion and ion-water interactions
J. Song, M. Kim, T. Kang, S. Han, Phys. Chem. Chem. Phys., 17 (2015) 8306-8322
PMCID: PMC4656249
DOI: 10.1039/C4CP05992A
Nanometer-Scale Water and Proton Diffusion Heterogeneities across Water Channels in Polymer Electrolyte Membranes
J. Song, O. H. Han,  S. Han, Angew. Chem., 54 (12) (2015) 3615-3620
PMCID: PMC4450673
DOI: 10.1002/anie.201408318

2015 Book Chapter

Methods in Enzymology: Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions - Part B
Edited by: P. Z. Qin, K. Warncke

Vol. 564, Elsevier Inc. (2015)

Overhauser Dynamic Nuclear Polarization Studies on Local Water Dynamics
I. Kaminker, R. Barnes, and S. Han
PMID: 26477261
DOI: 10.1016/bs.mie.2015.06.040

Protein NMR - Modern Techniques and Biomedical Applications
Edited by: Lawrence Berliner

Vol. 32, Springer (2015) 43-74

Mapping Out Protein Hydration Dynamics by Overhauser Dynamic Nuclear Polarization
C. Cheng, J. Song, J. Franck, S. Han
DOI: 10.1007/978-1-4899-7621-5_2

2014 Journal Articles

Local water diffusivity as a molecular probe of surface hydrophilicity 
J. Song, B. Allison, S. Han, MRS Bull., 39 (12) (2014) 1082-1088
DOI: 10.1557/mrs.2014.254
Cholesterol Enhances Surface Water Diffusion of Phospholipid Bilayers
C. Y. Cheng, L. Olijve, R. Kausik, S. Han, J. Chem. Phys., 141 (22D513) (2014)
PMCID: PMC4201661
DOI: 10.1063/1.4897539
Intrinsic Surface-Drying Properties of Bioadhesive Proteins
Y. Akdogan, W. Wei, K. Huang, Y. Kageyama, E. W. Danner, D. R. Miller, N. R. Martinez Rodriguez, J. H. Waite, S. Han, Angew. Chem., 126 (42) (2014) 11435-11438
PMCID: PMC4198389
DOI: 10.1002/ange.201406858   Featured in Nature Materials | Research Highlights
Probing water density and dynamics in the chaperonin GroEL cavity
J. Franck, M. Sokolovski, N. Kessler, E. Matalon, M. Gordon-Grossman, S. Han, D. Goldfarb, A. Horovitz, J. Am. Chem. Soc., 136 (26) (2014) 9396-9403
PMCID: PMC4091268
DOI: 10.1021/ja503501x
Specific Ions Modulate Diffusion Dynamics of Hydration Water on Lipid Membrane Surfaces
J. Song, J. Franck, P. Pincus, M.W. Kim, S. Han, J. Am. Chem. Soc., 136 (6) (2014) 2642-2649
PMCID: PMC3985948
DOI: 10.1021/ja4121692

2013 Journal Articles

Fluidity and Water in Nanoscale Domains Define Coacervate Hydrogels
J.H. Ortony, S.H. Choi, J.M. Spruell, J.N. Hunt, N.A. Lynd, D.V. Krogstad, V.S. Urban, C.J. Hawker, E.J. Kramer, S. Han, Chemical Sciences 5 (2013) 58-67
DOI: 10.1039/C3SC52368C
Hydration Dynamics as an Intrinsic Ruler for Refining Protein Structure at Lipid Membrane Interfaces
C.Y. Cheng, J. Varkey, M.R. Ambroso, R. Langen, S. Han, Proc. Natl. Acad. Sci. 110 (42) (2013) 16838–16843
PMCID: PMC3800990
DOI: 10.1073/pnas.1307678110
Quantitative cw Overhauser Dynamic Nuclear Polarization for the Analysis of Local Water Dynamics
J. M. Franck, A. Pavlova, J.A. Scott, S. Han, Prog. Nucl. Magn. Reson. 74 (2013) 33-56
PMCID: PMC3798041
DOI: 10.1016/j.pnmrs.2013.06.001
Asymmetric Collapse in Biomimetic Complex Coacervates Revealed by Local Polymer and Water Dynamics
J.H. Ortony, D.S. Hwang, J.M. Franck, J.H. Waite, S. Han, Biomacromolecules, 14(5) (2013) 1395-1402
PMCID: PMC4090114
DOI: 10.1021/bm4000579
Nonlinear Scaling of Surface Water Diffusion with Bulk Water Viscosity of Crowded Solutions
J.M. Franck, J.A. Scott, S. Han, J. Am. Chem. Soc., 135(11) (2013) 4175-4178
DOI: 10.1021/ja3112912

2012 Journal Articles

Nature of Interactions between PEO-PPO-PEO Triblock Copolymers and Lipid Membranes: The Role of Hydration Dynamics Revealed by Dynamic Nuclear Polarization
C. Cheng, J. Wang, R. Kausik, K. C. Lee, S. Han, Biomacromolecules, 13(9) (2012) 2624-2633
DOI: 10.1021/bm300848c
Hyperpolarized Water as an MRI Contrast Agent
M. D. Lingwood, T. Siaw, N. Sailasuta, O. A. Abulseoud, H. R. Chan, B. D. Ross, P. Bhattacharya, S. Han, , Radiology, 265 (3) (2012) 418-425
An ultrasensitive tool exploiting hydration dynamics to decipher weak lipid membrane–polymer interactions
C. Cheng, J. Wang, R. Kausik, K. C. Lee, S. Han, J. Magn. Reson. 215 (2012) 115-119
DOI: 10.1016/j.jmr.2011.12.004

2011 Journal Articles

Site-Specific Hydration Dynamics in the Nonpolar Core of a Molten Globule by Dynamic Nuclear Polarization of Water
B.D. Armstrong, J. Choi, C. Lopez, D. A. Wesener, W. Hubbell, S. Cavagnero, S. HanJ. Am. Chem. Soc.133 (2011) 5987–5995
PMCID: PMC3095581
DOI: 10.1021/ja111515s
Dynamics and State of Lipid Bilayer-internal Water Unraveled with Solution State 1H Dynamic Nuclear Polarization
R. Kausik, S. HanPhys. Chem. Chem. Phys. (2011) 13, 7732-7746
DOI: 10.1039/c0cp02512g
Probing the Hydration Water Diffusion of Macromolecular Surfaces and Interfaces
J. H. Ortony, C.-Y. Cheng, R. Kausik, A. Pavlova, J. Hunt, S. HanNew J. Phys.13 (2011) 015006 (15pp)
DOI: 10.1088/1367-2630/13/1/015006

2010 Journal Article

Continuous Flow Overhauser Dynamic Nuclear Polarization of Water in the Fringe Field of a Clinical Magnetic Resonance Imaging System for Authentic Image Contrast
M. D. Lingwood, T. A. Siaw, N. Sailasuta, B. D. Ross, P. Bhattacharya and S. HanJ. Magn. Reson. 205 (2) (2010) 247-254
DOI: 10.1016/j.jmr.2010.05.008

2009 Journal Articles

Ultrasensitive Detection of Interfacial Water Diffusion on Lipid Vesicle Surfaces at Molecular Length Scales
R. Kausik, S. Han.
J. Am. Chem. Soc. 131 (51) (2009) 18254-18256
DOI: 10.1021/ja9060849
Local Water Dynamics in Coacervated Polyelectrolytes Monitored through Dynamic Nuclear Polarization-Enhanced 1H NMR
R. Kausik, A. Srivastava, P.A. Korevaar, G. Stucky, J.H. Waite, S. HanMacromolecules 42 (19) (2009) 7404–7412
PMCID: PMC2929756
DOI: 10.1021/ma901137g
Site-specific Dynamic Nuclear Polarization of Hydration Water as a Generally Applicable Approach to Monitor Protein Aggregation
A. Pavlova, E.R. McCarney, D.W. Peterson, F.W. Dahlquist, J. Lew, S. HanPhys. Chem. Chem. Phys. (PCCP) 11 (2009) 6833-6839
PMCID: PMC3153360
DOI: 10.1039/b906101k
Overhauser Dynamic Nuclear Polarization To Study Local Water Dynamics
B.D. Armstrong, S. Han, J. Am. Chem. Soc. 131 (13) (2009) 4641-4647
DOI: 10.1021/ja809259q
Study of Local Diffusion Coefficients of the Hydration Layer of Lipid Vesicle Bilayers
R. Kausik, B. D. Armstrong, S. Han, Diffusion Fundamentals 10 (2009) 27.1-27.4
PMCID: PMC3985948
DOI: 10.1021/ja4121692

2008 Journal Articles

Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance and Electron Spin Resonance Studies of Hydration and Local Water Dynamics in Micelle and Vesicle Assemblies
E. R. McCarney, B.D. Armstrong, R. Kausik, S. HanLangmuir. 24 (18) (2008) 10062-10072
DOI: 10.1021/la800334k
Dynamic Nuclear Polarization Studies of Local Water Dynamics in Soft Molecular Assemblies at 9.8 GHz 
S. Han, E. R. McCarney, B.D. ArmstrongAppl. Magn. Reson. 34 (3-4) (2008) 439-451
DOI: 10.1007/s00723-008-0135-3
Local Hydration Dynamics in Soft Matter by Dynamic Nuclear Polarization of 1H-water
B. D. Armstrong, R. Kausik, S. Han, AIP Conf. Proc. 1081 (2008) 14-17
DOI: 10.1063/1.3058535