Han Research Group - Members

  • Undergraduate Student Researcher

 

My main research goal is to understandthe effect of surfactants and hydration on membrane protein functions. We are currently studying the membrane protein proteorhodopsin (PR) because it is easily characterized by its optical properties and is a good model protein for other membrane proteins. We are aiming to modulate PR by adjusting the external and internal surface hydration while in lipid vesicles using different surface active species.

  • (626) 283-0587
  • PSBN 4650A
  • Undergraduate Student Researcher

 

Andrew is working on elucidating the pathway of the tau protein’s aggregation into fibers, the cause of neurodegenerative diseases known as Tauopathies, including Alzheimer's disease. He assists with DEER spectroscopy distance measurements, ThT fluorescence, and small peptide production using molecular biology. In addition, he is in charge of creating tau mutants via site-directed mutagenesis, expressing and purifying these mutants, and preparing them for magnetic resonance experiments. One of his interests lies in optimizing spin-labelling efficiency for doubly spin-labelled IDPs, which could cut the time of DEER experiments in half. In doing this, he models the kinetics for, and studies the effects of solvent conditions on, multiple chemical reactions.

  • Undergraduate Student Researcher
  • Undergraduate Student Researcher
  • Undergraduate Student Researcher