Present: Associate Professor, Materials Science and Engineering Department, İzmir Institute of Technology, Turkey
Present: Senior Online Content Developer, The MathWorks
Present: Research Associate, Gritstone Oncology
Present: Senior Research Scientist, Colgate-Palmolive
Jessica's research in the Han Lab focused on high field electron paramagnetic resonance for the study of biological systems. This research helped build a better understanding of the processes that are important for the systems of spins at high field, aiming to develop new methods for styding biological systems. Jessica was developing a new tool for measuring distances in membrane proteins that will enhance their study of protein structure and dynamics. Under Mark Sherwin's guidance, she also helped develop the UCSB electron free laser as a tool for high field EPR.
Present: Design Verification Test Engineer III, Karl Storz Imaging
Present: Postdoctoral Researcher, University of Colorado, Boulder (Advisor: Prof. Thomas Perkins)
Neil focuses on tau protein which aggregates to form long fibers inside neurons in the brain. He works on understanding the early structural mechanism of the tau aggregation pathway. Tau aggregation is known to be associated with several neurodegenerative diseases known as Tauopathies which also include Alzheimer’s disease. By using double electron electron resonance (DEER), Neil is able to look at conformational changes both before and after inducing aggregation. Through tracking and characterizing specific conformational intermediates, it could be possible to locate structurally distinct targets for the treatment of tau related diseases.
Present: Project Manager, Infineon Technologies, Germany
Present: Assistant Professor, Chemistry Department, Syracuse University
Present: Postdoctoral Researcher, National Institutes of Health
Present: Founder and CEO of OTOjOY LLC
Present: Senior Research Scientist, Schlumberger-Doll Research
Present: Graduate Student Researcher, NSF Fellow, Stanford University (Advisor: Prof. Rajat Rohatgi)
Present: Assistant Professor, St. Mary's College of California
Alicia’s research focuses on instrument design and pushing the technique of NMR, DNP and EPR, with a specific focus designing an MAS-NMR probe that has DNP and EPR capabilities at temperatures below 90 K. Encompassed in this probe design research are fundamental studies on quantifying absolute enhancement factors from various nitroxide radicals and how the electron spin dynamics affect the DNP mechanism, particularly under magic angle spinning NMR. This work also involves applications to heterogeneous catalytic materials, where surface enhanced NMR through DNP can help differentiate the surface species from the bulk of a material.
Present: Postdoctoral Researcher, Centre de Résonance Magnétique Nucléaire (CMRN), Lyon, France (Advisor: Prof. Anne Lesage)
Present: Principal Scientist, Korimako Chemical Limited, New Zealand
Present: Research Associate - Formulation Development, Regeneron Pharmaceuticals, Inc.
Present: Assistant Professor, Massachusett Institute of Technology
Present: Senior Scientist, Abzena
- Past Member (Postdoctoral Researcher)
Present: Foreign Affairs Officer and AAAS Science and Technology Policy Fellow, U.S. Department of State
Nikki works on characterizing pharmaceutically relevant membrane protein complexes to link changes in structure and dynamics to function. Namely, she works with a G protein-coupled receptor called the adenosine A2a receptor to elucidate structural details and functional consequences of homo-dimerization. The A2a receptor regulates cardiac function and several processes within the central nervous system; the outcome of this research will facilitate improved rational drug design to target A2a receptor oligomers in the treatment of disorders such as inflammation, fibrosis, schizophrenia and Parkinson's disease.
Alex's research focuses on hydration on a molecular level. The question he is most concerned with is how and why are hydrophilic surfaces hydrated in both biological systems as well as non-biological or inorganic systems? He is working on solving this mystery by performing DNP measurements and surface force measurements. Apart from this, he works on the correlattion of measurements of water diffusivity with surface forces specifically for hydrated hydrophilic surfaces.
Present: Instructor, Elite Educational Institute
Present: NMR R&D Scientist, JEOL USA
Present: Associate Director, R&D, Pacira Pharmaceuticals, Inc.
Till worked on a project on hardware design to run ODNP on fuel cells. He and Songi Han were attempting to analyze conduction pathways in polyelectrolyte membranes with the help of ODNP. They hoped to better understand the difference between the surface (backbone) diffusion and the bulk diffusion using the ODNP. By changing those diffusion behaviors and understanding how membrane diffusion works, they built up the base to obtain a higher efficiency for diffusion through the membrane.