Tau Protein Aggregation Publications

2018 Journal Articles

Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer’s disease filaments
Y. Fichou, M. Vigers, A. K. Goring, N. A. Eschmann, S. Han, Chem. Commun.54 (2018), 4573-4576.
DOI: 10.1039/C8CC01355Aa

2017 Journal Articles

Methods in Cell Biology

Conformation-based assay of tau protein aggregation
Y. Fichou, N.A. Eschmann, T.J. Keller, S. Han, Methods Cell Biol., 141 (2017) 89-112.
DOI:10.1016/bs.mcb.2017.06.008

PLOS Biology May 2017

RNA Stores Tau Reversibly in Complex Coacervates
X. Zhang, N.E. Eschmann, Y. Lin, H. Zhou, J. Rauch, I. Hernandez, E. Guzman, K.S. Kosik, S. Han, PLOS Biol., 15 (7(2017) e2002183.
DOI:10.1371/journal.pbio.2002183. PMID: 28683104. PMCID: PMC5500003

Also published in bioRxiv: 
DOI:10.1016/

Highlighted in:

http://www.news.ucsb.edu/2017/018072/biophysical-smoking-gun

Scientific Reports Signature of an aggregation-prone conformation of tau
N.A. Eschmann, E.R. Georgieva, P. Ganguly, P.P. Borbat, M.D. Rappaport, Y. Akdogan, J.H. Freed, J.E. Shea, S. Han, Sci. Rep., 7 (20171-10 
DOI:10.1038/srep44739. PMID: 28303942 PMCID: PMC5356194.

2016 Journal Article

PNAS Protein structural and surface water rearrangement constitute major events in the earliest aggregation stages of tau
A. Pavlova, C. Cheng, M. Kinnebrew, J. Lew, F. Dahlquist, S. Han, Proc. Natl. Acad. Sci., 113 (2) (2016) E127-E136
PMCID: PMC4720316
DOI:10.1073/pnas.1504415113 

2015 Journal Article

Journal of Physical Chemistry B Tau Aggregation Propensity Engrained in Its Solution State
N. Eschmann, T. Do, N. LaPointe, J. Shea, S. Feinstein, M. Bowers, S. Han, J. Phys. Chem., 119 (45) (2015) 14421–14432
PMCID: PMC4645975
DOI: 10.1021/acs.jpcb.5b08092